李娇娇，女, 博士，1986年12月生, 云南省祥云县人。现任尊龙凯时环境科学与工程系副教授，硕士生导师。
主要从事污染生态学、生态毒理学方面的研究。先后承担国家级、省级等多项项目；在国内外核心刊物上发表学术论文10余篇，其中SCI刊物上发表10余篇。
在生态毒理学及应用方面取得进展，主要包括以下几个方面：
（1）水华蓝藻次生代谢物生态毒理及风险分析；
（2）有害结局路径和效应导向分析集合下的环境毒理体系构建、生物标志物锁定、水体污染源解析；
（3）从个体、免疫器官、病理组织、免疫细胞、免疫分子等多层次阐述水华蓝藻胞外分泌物对生物体的免疫毒性机制、致畸性机制等。
（4）新型碳点材料对新污染物降解的研发。
联系方式
E-mail: jiaojiaoli@cqlty.com
学历
l 2005.08－2010.07: 昆明医科大学学习，临床医学专业，获理学学士学位
l 2012.08－2017.08: 美国佛罗里达国际大学学习，生物医学科学专业，获理学博士（PhD）学位
近十年主持或承担的科研项目
l 2023-2027：云南省兴滇英才科研经费支持项目:基于有害结局路径（AOP）框架对水体复合污染物的监测和风险评估,项目负责人,经费63万元；
l 2022-2025：云南省科技厅应用基础研究面上项目:水华蓝藻胞外分泌物对滇池金线鲃的毒性效应及机制研究,项目负责人,经费10万元；
l 2022-2024：国家基金委青年基金项目:水华蓝藻胞外分泌物及其主要成分植物鞘氨醇有害结局路径研究,项目负责人,经费30万元；
l 2021-2023：云南省科技厅应用基础研究青年项目:铜绿微囊藻胞外分泌物中维A酸对滇池金线鲃胚胎的致畸性研究,项目负责人,经费5万元。
近十年发表主要学术论文
1. Sen Zhao, Xuexiu Chang, Jun Li, Yanhua Zhu, Xiaofu Pan, Zexiang Hua, Jiaojiao Li*. The two-way immunotoxicity in native fish induced by exudates of Microcystis aeruginosa: Immunostimulation and immunosuppression. J Hazard Mater. 2024 Jan 5;461:132554.
2. Jiaojiao Li, Xinshuo Chen, Shixiang Zhao, and Jian Chen. Arsenic-Containing Medicine Treatment Disturbed the Human Intestinal Microbial Flora. Toxics. 2023, 11, 458.
3. Chunxiao Sun, Xuexiu Chang, Hugh J MacIsaac, Jiayao Wen, Lixing Zhao, Zhi Dai, Jiaojiao Li*. Phytosphingosine inhibits cell proliferation by damaging DNA in human cell lines. Ecotoxicol Environ Saf. 2023 Mar 29;256:114840.
4. Jiaojiao Li, Jiayao Wen, Chunxiao Sun, Yuan Zhou, Jun Xu, Hugh J MacIsaac, Xuexiu Chang, Qinghua Cui. Phytosphingosine-induced cell apoptosis via a mitochondrially mediated pathway. Toxicology. 2022 Dec;482:153370.
5. Jiaojiao Li*, Chunxiao Sun, Wenwen Cai, Barry P. Rosen, Jian Chen. Insights into S-adenosyl-L-methionine (SAM)-dependent methyltransferase related diseases and genetic polymorphisms. Mutation Research/Reviews in Mutation Research. 2021, 108396, ISSN 1383-5742.
6. Li, J. J.*, L. Yang, C . P. Miao, Y. J. Teng, Z. H. Fu, C. L. Cheng, X. X. Chang, Y. Qian, and L. X. Zhao. 2021. Impact of rhizosphere microorganisms on arsenic (As) transformation and accumulation in a traditional Chinese medical plant. Environ Sci Pollut Res Int. 2021 Nov;28(43):60923-60934.
7. Zhili Peng*，Tianshu Zhao，Yiqun Zhou，Shanghao Li，Jiaojiao Li*，Roger M Leblanc*. Bone Tissue Engineering via Carbon‐based Nanomaterials. Advanced Healthcare Materials 2020, 9, 1901495.
8. Charles Packianathan, Jiaojiao Li, Palani Kandavelu, Banumathi Sankaran, and Barry P. Rosen*，Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S‐Adenosylmethionine Methyltransferase Reaction，ACS Omega 2018, 3, 3104−3112.
9. Jiaojiao Li，Charles Packianathan，Toby G. Rossman，Barry P. Rosen, Nonsynonymous Polymorphisms in the Human As3mt Arsenic Methylation Gene: Implications for Arsenic Toxicity, Chemical Research in Toxicology, 2017, 30 (7): 1481-1491.
10. Jiaojiao Li，Goutam Mandal，Barry P. Rosen, Expression of Arsenic Resistance Genes in the Obligate Anaerobe Bacteroides Vulgatus Atcc 8482, a Gut Microbiome Bacterium, Anaerobe, *2016, 39: 117-123.
11. Jiaojiao Li，Shashank S. Pawitwar，Barry P. Rosen, The Organoarsenical Biocycle and the Primordial Antibiotic Methylarsenite, Metallomics, 2016, 8 (10): 1047-1055.
12. Zhili Peng, Jiaojiao Li, Shanghao Li, Joel Pardo, Yiqun Zhou, Abdulrahman O. Al-Youbi,Abdulaziz S. Bashammakh, Mohammad S. El-Shahawi, Roger M. Leblanc, Quantification of Nucleic Acid Concentration in the Nanoparticle or Polymer Conjugates Using Circular Dichroism Spectroscopy, Analytical Chemistry, 2018, 90 (3): 2255-2262.
13. Charles Packianathan, Jiaojiao Li, Palani Kandavelu, Banumathi Sankaran, and Barry P. Rosen，Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S‐Adenosylmethionine Methyltransferase Reaction，ACS Omega 2018, 3, 3104−3112.
14. Jian Chen，Jiaojiao Li，Xuan Jiang，Barry P. Rosen, Conserved Cysteine Residues Determine Substrate Specificity in a Novel as(Iii)-S-Adenosylmethionine Methyltransferase from Aspergillus Fumigatus, Molecular Microbiology, 2017, 104 (2): 250-259. …….
