张效伟，男，1978年4月生，教授。教育部长江学者特聘教授（2023）、万人计划科技创新领军人才（2019）、青年长江学者（2016）、国家自然科学优青（2013）。国家重点研发计划项目首席科学家。
长期从事生态环境风险防控理论与方法研究，提出了基于组学的生态风险与生态系统修复评估策略，开发了环境 DNA 的生物多样性监测与生态系统健康评估新方法，在Nature Commun， ES&T，Water Res和 Global Change Biology等上发表SCI论文200余篇，出版学术专著3部。获得发明专利10余项、其中商业转让2项。
联系方式： zhangxw@cqlty.com
Orcid ID: https://orcid.org/0000-0001-8974-9963
Prof. Xiaowei Zhang holds a Distinguished Professorship from the School of Ecology and Environment Science, Yunnan University. He is mainly engaged in the research on the theory and methods of aquatic ecosystem security and health, focusing on the development of environmental DNA technologies in Biodiversity Conservation and Ecosystem Restoration. Currently his research group is devoted in Spatiotemporal Intelligence of Eco-Environment through eDNA: Utilizing cutting-edge community eDNA data to gain insights into ecological and environmental dynamics over time and space. He has published more than 200 SCI papers (H-index=50) and 3 books. He serves as Associate Editor of Environmental Science & Technology.
Email: zhangxw@cqlty.com
Orcid ID: https://orcid.org/0000-0001-8974-9963
研究领域（Research Areas）
主要从事水生态安全与健康理论与方法学研究，重点方向包括：化学品预测毒理学，环境 DNA生物多样性监测与生态系统健康评估。
Ø Developing eDNA technologies and instruments for biodiversity monitoring in aquatic ecosystems (rivers，lake, coastal environment)
Ø Developing innovations in wastewater surveillance for public health monitoring.
Ø Ecotoxicology of emerging pollution and risk management
教育经历（Education）
●2004年—2008年， 美国密歇根州立大学，动物学环境毒理学（博士）
●2006年—2007年， 美国密歇根州立大学，应用统计学（硕士）
●2000年—2003年， 香港城市大学，环境科学（硕士）
●1996年—2000年， 南京大学，环境科学与工程（本科）
Ø 2004-2008: Ph.D. in Zoology & Environmental Toxicology, Michigan State University.
Ø 2007-2007: Master’s Degree in Applied Statistics, Michigan State University.
Ø 2000-2003: Master’s Degree in Environmental Science, City University of Hong Kong.
Ø 1996-2000: Bachelor’s Degree in Environmental Science & Technology, Nanjing University.
工作经历(Employment History)
●2024-今：尊龙凯时教授
●2009-2024：南京大学环境学院教授，博导
●2009-2010：加拿大萨斯喀彻温大学毒理学中心，项目科学家
●2008-2009： 加拿大萨斯喀彻温大学毒理学中心，博士后
●2003-2004 ：美国密歇根州立大学，国家食品安全和毒理学研究中心，访问学者
Ø 2024–Present: Professor, School of Ecology and Environmental Sciences, Yunnan University.
Ø 2009–2024: Professor and Doctoral Supervisor, School of the Environment, Nanjing University.
Ø 2009–2010: Project Scientist, Toxicology Centre, University of Saskatchewan, Canada.
Ø 2008–2009: Postdoctoral Researcher, Toxicology Centre, University of Saskatchewan, Canada.
Ø 2003–2004: Visiting Scholar, National Food Safety and Toxicology Center, Michigan State University, USA.
主持科研项目(Research Projects)
●2022.11-2026.4：国家重点研发计划项目，长江水生态系统重要指示种及生态系统健康评估（2022YFC3202100），1480万，主持；
●2022.11-2026.4：国家重点研发计划项目课题，长江流域重要指示种数据库及生态系统健康评估体系构建（2022YFC3202101）355万，主持；
●2022.09-2024.08：江苏省生态环境科研项目，环境 DNA 在线自动采集仪和智慧分析系统的转化与推广（2022001），300万，结题，主持；
●2020.01-2023.12：国家自然科学基金，面上项目，41977206，浮游动物生物毒性跨物种敏感性预测研究，60万，结题，主持
●2013.10-2018.12：国家欧盟委员会，FP7课题，603427-2，Solutions for present and future emerging polluta nts in land and water resources management，结题，中方主持；
●2014.01-2016.12：国家自然科学基金“优秀青年基金”项目，21322704，化学品毒理基因组学， 100万元，结题，主持；
●2013.10-2016.10：江苏省科技厅，“杰出青年基金”项目，SBK201310181，研发基于DNA条形码的化学品污染生态监测和风险预测技术， 100万元，结题，主持；
●2013.01-2015.12：科技部，“863”项目课题，2013AA06A309，典型沿江化工区风险甄别与控制综合示范, 1180万，结题，主持。
Professor Zhang has recently led significant national and international research projects, contributing to the advancement of ecological health assessments and environmental risk management. Below are some key highlights:
Ø Yangtze River Ecosystem Health Assessment (2022YFC3202100, 2022YFC3202101)
Under China’s National Key Research and Development Program, these projects focus on developing a comprehensive evaluation of critical indicator species and ecosystem health within the Yangtze River basin. The research involves constructing a detailed database and assessment system to support ecological restoration efforts. With a total funding of ¥15 million, these projects span from 2022 to 2026 and aim to provide groundbreaking methodologies for monitoring and safeguarding aquatic biodiversity.
Ø Predictive Toxicology for Zooplankton (Grant 41977206)
Supported by the National Natural Science Foundation of China, this project (2020-2023) investigated cross-species sensitivity in zooplankton bio-toxicity. With ¥600,000 in funding, the study yielded insights into interspecies variability and predictive models for ecological risk, advancing our understanding of aquatic toxicology.
Ø Development and Application Environmental DNA Technologies (2022001)
Focused on the practical applications of environmental DNA (eDNA), this project, funded by the Jiangsu Provincial Department of Ecology and Environment, aims to develop smart analysis systems and automated collection devices for eDNA monitoring. With ¥3 million in funding, it facilitates real-time ecological data acquisition and supports environmental decision-making.
Ø Foundational Contributions to Toxicogenomics
Earlier works, including the National Natural Science Foundation’s Excellent Young Scientist Grant (2014-2016, ¥1 million) and a pivotal 863 Program project (2013-2015, ¥11.8 million), laid the groundwork for Professor Zhang’s research trajectory. These projects addressed chemical risk assessment and the ecological safety of industrial regions, introducing genomic tools and systemic approaches to risk evaluation.
Ø International Collaboration on Emerging Pollutants
Through the European Union’s FP7 program, Professor Zhang co-led the Chinese team in a multinational initiative (2013-2018) addressing emerging pollutants in land and water management. This collaborative research provided sustainable solutions for mitigating pollution impacts across diverse ecosystems.
学术兼职 (Professional Services)
●2024-至今, SCI期刊 ES&T，Associate Editor
●2019-至今，国家环境基准专家委员会委员
●2018-至今, 国际SETAC学会亚太分会，董事会成员
●2016-至今, 中文核心期刊《生态毒理学报》，副主编
●2014-至今, SCI期刊 Environmental Toxicology & Chemistry, Editor
●2019-2020, SCI期刊 Environmental Research，Associate Editor
●2011-2012, SCI期刊 Chemosphere，Associate Editor
Ø 2024–Present: Associate Editor, SCI journal Environmental Science & Technology (ES&T).
Ø 2019–Present: Member, National Environmental Standards Expert Committee, China.
Ø 2018–Present: Board Member, Asia-Pacific Branch of the International Society of Environmental Toxicology and Chemistry (SETAC).
Ø 2016–Present: Deputy Editor, Chinese core journal Journal of Ecotoxicology.
Ø 2014–Present: Editor, SCI journal Environmental Toxicology & Chemistry.
Ø 2019–2020: Associate Editor, SCI journal Environmental Research.
Ø 2011–2012: Associate Editor, SCI journal Chemosphere.
获奖情况 (Awards and Honors)
●2023年获中国毒理学会“中国毒理学替代法发展奖”；
●2020年作为指导教师指导学生获中国国际互联网+大学生创新创业大赛金奖；
●2020年中国生态环境部“国家生态环境保护专业技术领军人才”；
●2019年美国化学学会环境领域 ES&T “Early Career Scientists”；
●2019年获国家高层次人才特殊支持计划“科技创新领军人才”；
●2018年中国环境科学学会首届“青年科学家金奖”获得者；
Ø China Toxicology Society “Development Award for Alternative Methods in Toxicology” (2023): Recognizing his contribution in technology innovation on new methodology approach in toxicology
Ø Gold Medal Advisor for the “China International Internet+ College Student Innovation and Entrepreneurship Competition” (2020) Recognizing exceptional mentorship on college student innovation.
Ø National Ecological Environmental Protection Professional and Technical Leading Talent, Ministry of Ecology and Environment, China (2020): For achievement in science and technology innovation in Chinese Ecological Environmental Protection.
Ø Early Career Scientist, Environmental Science & Technology, American Chemical Society (2019): This prestigious recognition aims to encourage early-career scientists to continue driving forward research in critical areas of environmental science
Ø National High-Level Talent Special Support Program – Leading Talent in Scientific and Technological Innovation (2019)
Ø Youth Scientist Gold Award, Chinese Society for Environmental Sciences (2018)
主要著作和教材 (Books and Chapters)：
1、张效伟 等著，《化学物质毒理基因组学测试理论与方法》，科学出版社，2024，ISBN:9787030781741。
2、张效伟 等著，《环境 DNA 生物监测理论与技术》，科学出版社，2023，ISBN:9787030747327。
3、尹大强、刘树深、桑楠、张效伟 著，《持久性有机污染物的生态毒理学》，科学出版社，2019，ISBN: 9787030603029。
4、于红霞、王连生、史薇、张效伟 主编，《有机污染化学》（第二版），科学出版社，2024，WBS: 12-02540-004。
5、孔志明、李梅、张效伟、张徐祥 主编，《环境毒理学》（第六版）国家级规划教材，南京大学出版社， 2017， ISBN: 9787305184703。
6、 参编《环境生物学》（教材），科学出版社，2022，ISBN:9787030640284
7、参编《体外与预测毒理学》，北京大学医学出版社有限公司，2021，ISBN:9787565916373
8、Zhang X., Wang P., Xia P. (2020). Dose-Dependent Transcriptomic Approach for Mechanistic Screening in Chemical Risk Assessment. In book: A New Paradigm for Environmental Chemistry and Toxicology, Springer. DOI: 10.1007/978-981-13-9447-8_4
9、Zhang, X., Giesy J., Hecker, M. (2013). Cell Lines in Aquatic Toxicology. In: J.F. Férard, C. Blaise, (eds.): Encyclopedia of Aquatic Ecotoxicology，Springer Publishers, Dordrecht, The Netherlands. pp 259-268
10、Zhang, X., Wiseman S, Giesy J. (2012) Toxicology of Water. In: A. Luch (ed): Molecular, Clinical and Environmental Toxicology Vol. III. Environmental Toxicology. Birkhäuser, Berlin. Germany.101:21-46. doi: 10.1007/978-3-7643-8340-4_2.
授权发明专利 (Patents)
1、Zhang X.*, Hecker, M. and Giesy, J.P. Steroidogenesis modified cells and methods for screening for endocrine disrupting chemicals (Patent Number: US 08299238)
2、张效伟、杨雅楠、夏普，一种检测鱼腥草磷代谢相关酶基因表达量引物及应用与方法，ZL201510622133.7
3、张效伟、洪陵成、刘萌斐、杨江华, 一种污水生物毒性在线监测预警装置，ZL201510780823.5
4、张效伟、杨江华，浮游动物rrnL基因扩增引物及其筛选方法和应用及应用方法，ZL201410736863.5
5、张效伟、夏普，化学品安全信息快速查询和全周期追踪数码标签系统，ZL201510220542.4
6、张效伟、杨江华，一种利用高通量测序构建浮游动物条形码数据库的方法，ZL201410748206.2
7、张效伟、刘萌斐、杨江华,一种水生生物样品在线自动采集及保存装置, ZL201510766516.1
代表性论文 (Selected Publications)
1、Zhang X. Environmental DNA Shaping a New Era of Ecotoxicological Research. Environ Sci Technol. 2019 53(10):5605-5612. (Invited Perspective)
2、Zhang X, Xia P, Wang P, Yang J, Baird D. 2018. Omics advances in Ecotoxicology. Environ Sci Technol. 52(7):3842-3851. (Invited Feature)
3、Liu YY, Yu NY, Fang WD, Tan QG, Ji R, Yang LY, Wei S, Zhang X, Miao AJ. Photodegradation of carbon dots cause cytotoxicity. Nat Commun. 2021;12(1):812.
4、Li F, Altermatt F, Yang J, An S, Li A, Zhang X. Human activities' fingerprint on multitrophic biodiversity and ecosystem functions across a major river catchment in China. Glob Chang Biol. 2020 Dec;26(12):6867-6879.
5、闫路, 苟潇, 夏普,张效伟等. 基于组学的污染物高通量毒理学筛查与风险评估. 科学通报, 2022, 67:
View Full publication list: https://orcid.org/0000-0001-8974-9963
英文期刊论文(Publications in the past years)：
1) Zhang Y, Qu Y, Liu K, Zhong W, Yang J, Altermat F. Zhang X*. Evaluating eDNA and eRNA metabarcoding for aquatic biodiversity assessment: From bacteria to vertebrates, Environ Sci Ecotechnol, 2024, 21, 100441.
2) Zhang, Y., Huang, D., Jin, X. Zhang X. Long-term wetland biomonitoring highlights the differential impact of land use on macroinvertebrate diversity in Dongting Lake in China. Commun Earth Environ 5, 32 (2024).
3) Mu, Y., Zhang, J., Yang, J., Wu, J., Zhang, Y.,Yu, H., Zhang, X*. Enhancing amphibian biomonitoring through eDNA metabarcoding. Molecular Ecology Resources, 2024, 00, e13931.
4) Li F*, Zhang Y, Altermatt F, Yang J, Zhang X*. Destabilizing Effects of Environmental Stressors on Aquatic Communities and Interaction Networks across a Major River Basin. Environ Sci Technol. 2023, 57(20):7828-7839.
5) Yang J, Zhang L, Mu Y, Wang J, Yu H, Zhang X*. Unsupervised biological integrity assessment by eDNA biomonitoring of multi-trophic aquatic taxa. Environ Int. 2023,175:107950.
6) Altermatt, F*, Carraro, L, Antonetti, M, Albouy, C, Zhang, Y, Lyet, A, Zhang, X*, & Pellissier, L*. Quantifying biodiversity using eDNA from water bodies: General principles and recommendations for sampling designs. Environmental DNA, 2023, 5, 671–682.
7) Zhang Y, Zhang X*, Li F, Altermatt F, Fishing eDNA in one of the world's largest rivers: a case study of cross-sectional and depth profile sampling in the Yangtze" Environ Sci Technol. 2023. 57 (51), 21691-21703
8) Lin Y, Li X, Zhang S, Yang Q, Zhang R, Zhang, X*. Congener Variation of Genetic Dependent-Developmental Toxicology in Two Emerging Classes of Dioxin-like Compounds. Environ Sci Technol. 2023 57 (51), 21650-21661
中文核心期刊论文 (Publications in Chinese)：
1.张丽娟,徐杉,赵峥,周小华,冯庆,杨江华,李飞龙,王志浩,张效伟*.环境 DNA宏条形码监测湖泊真核浮游植物的精准性[J].环境科学,2021.42(2):796-807.（封面论文）
2.彭颖,张瀚心,张效伟*.2021.定量有害结局路径(qAops)评估环境化学物质毒性的研究进展Ⅰ:模型构建与应用案例[J].生态毒理学报,16(03):1-13.
3.田明明,彭颖,张睿,张瀚心,张效伟*.2021.定量有害结局路径(qAop)评估环境化学物质毒性的研究进展Ⅱ:类二噁英物质及AHR-qAop[J].生态毒理学报,16(04):1-16.
4.周君薇、张丽娟、周宇昆、张效伟*.2021.实时荧光定量PCR技术在太湖蓝藻监测和评估中的应用[J].生态毒理学报,16(06):13-25.
5.闫路,苟潇,彭颖,高瑞泽,田明明,张效伟*.2021.基于3D体外培养模型的化学物质肝毒性预测研究进展.生态毒理学报（已接收）.
6.田明明,夏普,张效伟*.功能基因组学在环境化学品毒性机制研究中的应用[J] .生态毒理学报,2022,17(1):1-17.
7.苟潇,于洋,林军,张效伟*等.基于有害结局路径的化学物质计算毒理学研究[J].生态毒理学报,2022,17(1):313-324.
8.金珂,张丽娟,张伟,张效伟*等.基于环境DNA宏条形码的太湖流域底栖动物监测与生态健康评价[J].中国环境监测,2022(001):038.
9.姜山,张颜,李飞龙,张效伟,基于eDNA的硅藻群落时空异质性及生态健康评价[J/OL].环境科学.https://doi.org/10.13227/j.hjkx.202204019.
10.闫路,苟潇,夏普,张效伟等.基于组学的污染物高通量毒理学筛查与风险评估.科学通报,2022,67:
招贤纳士 (We Are Hiring)：
团队是在国家重大人才工程计划平台基础上建立的，致力于水生态安全与健康相关的基础和应用研究。团队在”水环境-水资源-水生态”交叉领域开展创新工作，拥有充足的科研经费和先进的实验设备，包括化学分析和基因组分析的硬软件仪器等。实验室空间充足，设施完善，为科研工作提供有力支持。
我们欢迎具有环境科学、生态学、材料科学、人工智能等相关背景和研究经验的多层次人才加入，共同探索水生态健康领域的前沿课题。
The team has been established under the framework of the National Major Talent Program and is dedicated to fundamental and applied research in water ecological safety and health. We focus on innovative studies at the intersection of “water environment–water resources–water ecology,” supported by ample funding and advanced laboratory equipment, including cutting-edge hardware and software for chemical and genomic analysis. The laboratory boasts ample space and comprehensive facilities, ensuring robust support for research endeavors.
We welcome talented individuals with backgrounds in environmental science, ecology, materials science, artificial intelligence, and related research experience to join us in exploring the frontiers of water ecological health.
Contact Information
Office Address:
Room 4224, School of Ecology and Environmental Sciences, Yunnan University, Chenggong Campus, Kunming, Yunnan Province, 650504, China.
Email: [zhangxw@cqlty.com]
